A Simple Key For modafinil norge Unveiled
A Simple Key For modafinil norge Unveiled
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Medisinen ble opprinnelig utviklet i Frankrike til bruk i det franske forsvaret. Den skulle brukes av det franske flyvåpenets soldater, slik at de skulle føle mindre tretthet og klare å konsentrere seg bedre om oppgavene sine.
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En gruppe legemidler som motvirker depresjon ved å øke konsentrasjonen av signalstoffene noradrenalin og serotonin i hjernen.
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Modafinil lessens Excessive sleepiness as a result of narcolepsy as well as other snooze disorders, like intervals of stopped respiration through rest (obstructive sleep apnea).
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It is clearly a possibility that modafinil could instantly act on enzymes in the brain’s free of charge-radical scavenging process (eg, glutathione peroxidase or superoxide dismutase) to right reduce cost-free-radical concentrations. For the reason that, reactive oxygen species feed back again positively about the mitochondrion to scale back ATP generation And perhaps improve totally free radical generation (Echtay et al 2002; Brookes et al 2004), this kind of mechanism could also account for modafinil’s capability to boost the cortical creatine-phosphocreatine pool (Pierard et al 1995).
For medisinbytte ved institusjoner henvises til §seven i Forskrift om legemiddelhåndtering for virksomheter og helsepersonell som yter helsehjelp
Jenner et al (2000) looked at the neuroprotective and anti-parkinsonian results of modafinil in monkeys addressed with MPTP. In a single examine they discovered which the MPTP induced parkinsonism signs or symptoms could possibly be enhanced with modafinil 11 months just after MPTP administration. Within a second research they click here found that modafinil administration with MPTP was unable to stop Original locomotor consequences of MPTP, but was in a position to revive locomotor exercise in two months.
Ferraro et al (1999) utilizing in vivo microdialysis and put up mortem high performance liquid chromatography found that modafinil boosts extracellular glutamate inside the medial preoptic and posterior parts of the hypothalamus, even so the area application of your GABAA receptor antagonist bicuculline, which lifted basal glutamate degrees, prevented an additional increase in glutamate from modafinil.
Inquire about reputable sorts of non-hormonal start Manage when employing this medication and for two months following the previous dose. If you turn out to be Expecting, speak to your medical professional without delay with regard to the dangers and benefits of this medication.
This is not a complete listing of feasible Uncomfortable side effects. In the event you see other effects not outlined higher than, contact your medical doctor or pharmacist.
That same yr, this group revealed One more paper which they described an experiment examining GABA and glutamate inside the thalamus and hippocampus, acquiring that modafinil greater glutamate in these Mind places, but didn't alter GABA stages in these areas (Ferraro et al 1997a).